Self assembled bi-functional peptide hydrogels with biomineralization-directing peptides
نویسندگان
چکیده
منابع مشابه
Templated biomineralization on self-assembled protein fibers.
Biological mineralization of tissues in living organisms relies on proteins that preferentially nucleate minerals and control their growth. This process is often referred to as "templating," but this term has become generic, denoting various proposed mineral-organic interactions including both chemical and structural affinities. Here, we present an approach using self-assembled networks of elas...
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Self-assembled biomaterials are an important class of materials that can be injected and formed in situ. However, they often are not able to meet the mechanical properties necessary for many biological applications, losing mechanical properties at low strains. We synthesized hybrid hydrogels consisting of a poly(γ-glutamic acid) polymer network physically cross-linked via grafted self-assemblin...
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A number of short peptides and larger proteins are able to self-assemble to form cross-b amyloid-like fibrils. These bsheet peptides have been increasingly explored as potentially useful bionanomaterials due to their propensity to spontaneously assemble to form large complex structures from simple monomers. An eight-residue fragment of the amyloidogenic Parkinson s disease related peptide a-syn...
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Energy transfer between a naphthalene-dipeptide and either a hosted dansyl acceptor or a co-assembling anthracene-dipeptide acceptor occurs on formation of a hydrogel by decreasing the pH.
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introduction: in the present study, we hypothesized that a novel approach to promote vascularization would be to create injectable three dimensional (3-d) scaffolds within growth factor that enhance the sustained release of growth factor and induce the angiogenesis. material and methods: we demonstrate that a 3-d scaffold can be formed by mixing of peptide-amphiphile (pa) aqueous solution with ...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2010
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2010.06.010